Tumor invasion as non-equilibrium phase separation
W. Kang, J. Ferruzzi, C.-P. Spatarelu, Y. L. Han, Y. Sharma, S. Koehler, J. P. Butler, D. Roblyer, M. H. Zaman, M. Guo, Z. Chen, A. F. Pegoraro, J. J. Fredberg
The paper shows tumor spheroids exhibit solid-like, fluid-like, and gas-like phases during invasion, with phase transitions influenced by cell type and matrix density.
bioRxiv · Apr 28, 2020 · PreprintBiophysics