Author

M. H. Zaman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 3 Cancer Biology· 3 Biophysics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:E. coli· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

I. Sutradhar· 4 shared C. Ching· 3 shared G. Higgins· 3 shared J. Ferruzzi· 3 shared T. Franz· 3 shared A. S. Khalil· 2 shared D. Desai· 2 shared D. Roblyer· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBioengineering

I. Sutradhar

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Metal Ions and their Effects on Antimicrobial Resistance Development in Wastewater

I. Sutradhar, P. Kalyan, K. Chukwu, A. L. K. Abia, J. Mbanga, D. H. Hamer, S. Essack, M. H. Zaman

The paper investigates how metal ions in wastewater affect antibiotic resistance development in E. coli by combining experimental data with computational modeling.

bioRxiv · Jun 16, 2023 · PreprintBioengineering

Impact of Zinc Pre-exposure on de novo Antibiotic Resistance Development

M. P. Suprenant, C. Ching, I. Sutradhar, N. Gross, J. E. Anderson, N. El Sherif, M. H. Zaman

This study shows that zinc pre-exposure before ciprofloxacin exposure in E. coli accelerates antibiotic resistance development, while combined exposure delays it, without causing genetic changes.

bioRxiv · Apr 10, 2023 · PreprintMicrobiology

Effects of Antibiotic Interaction on Antimicrobial Resistance Development in Wastewater

I. Sutradhar, C. Ching, D. Desai, Z. Heins, A. S. Khalil, M. H. Zaman

This study investigates how antibiotic interactions in wastewater affect antimicrobial resistance development in E. coli, finding that synergistic interactions suppress resistance while antagonistic interactions show ratio-dependent resistance development.

bioRxiv · Feb 10, 2023Bioengineering

Effect of paclitaxel treatment on cellular mechanics and morphology of human oesophageal squamous cell carcinoma in 2D and 3D environments

M. Kiwanuka, G. Higgins, S. Ngcobo, J. Nagawa, D. M. Lang, M. H. Zaman, N. H. Davies, T. Franz

This study examines how paclitaxel affects the stiffness and morphology of human oesophageal squamous cell carcinoma cells in 2D and 3D environments, finding increased stiffness in 2D but mixed results in 3D.

bioRxiv · Mar 6, 2022 · PreprintCancer Biology

An exploratory study on the role of the stiffness of breast cancer cells in their detachment from spheroids and migration in 3D collagen matrices

G. Higgins, J. E. Kim, J. Ferruzzi, T. Abdalrahman, T. Franz, M. H. Zaman

This study investigates how breast cancer cell stiffness changes during detachment from spheroids and migration in 3D collagen matrices, finding that decreased stiffness facilitates detachment and migration.

bioRxiv · Jan 21, 2021 · PreprintCancer Biology

Computational Model to Quantify the Growth of Antibiotic Resistant Bacteria in Wastewater

I. Sutradhar, C. Ching, D. Desai, M. Suprenant, E. Briars, Z. Heins, A. S. Khalil, M. H. Zaman

The paper develops a computational model to predict antibiotic resistant bacteria growth in wastewater, finding horizontal gene transfer and antibiotic interactions drive resistance more than chromosomal mutations.

bioRxiv · Oct 9, 2020Bioengineering

Epithelial layer unjamming shifts energy metabolism toward glycolysis

S. J. DeCamp, V. M. K. Tsuda, J. Ferruzzi, S. A. Koehler, D. Roblyer, J. T. Giblin, M. H. Zaman, S. T. Weiss, M. DeMarzio, C. Y. Park, N. C. Ogassavara, J. A. Mitchel, J. P. Butler, J. J. Fredberg

The paper shows that during epithelial layer unjamming, cells shift their metabolism toward glycolysis, even in regions without visible morphological changes.

bioRxiv · Jun 30, 2020Biophysics

Tumor invasion as non-equilibrium phase separation

W. Kang, J. Ferruzzi, C.-P. Spatarelu, Y. L. Han, Y. Sharma, S. Koehler, J. P. Butler, D. Roblyer, M. H. Zaman, M. Guo, Z. Chen, A. F. Pegoraro, J. J. Fredberg

The paper shows tumor spheroids exhibit solid-like, fluid-like, and gas-like phases during invasion, with phase transitions influenced by cell type and matrix density.

bioRxiv · Apr 28, 2020 · PreprintBiophysics

Cytoskeletal Tubulin Competes with Actin to Increase Deformability of Metastatic Melanoma Cells

G. Higgins, J. Peres, T. Abdalrahman, M. H. Zaman, D. Lang, S. Prince, T. Franz

This study shows that metastatic melanoma cells have increased fluidity and cytoskeletal components, which enhance motility while reducing stiffness compared to earlier disease stages.

bioRxiv · Feb 1, 2020Cancer Biology