The distribution of fitness effects of plasmid pOXA-48 in clinical enterobacteria
A. Fernandez-Calvet, L. Toribio-Celestino, A. Alonso-del Valle, J. Sastre-Dominguez, P. Valdes-Chiara, A. San Millan, J. DelaFuente
This study investigates the fitness effects of the plasmid pOXA-48 in clinical enterobacteria using CRISPR-Cas9 to cure plasmids, revealing mostly neutral effects with rare fitness costs or benefits.
bioRxiv · Jul 11, 2023 · PreprintMicrobiology