Author

A. Alonso-del Valle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:statistical model· 1

Frequent Co-Authors

A. San Millan· 4 shared J. DelaFuente· 3 shared R. Canton· 3 shared J. Rodriguez-Beltran· 2 shared L. Toribio-Celestino· 2 shared R. Leon-Sampedro· 2 shared R. Pena-Miller· 2 shared A. Fernandez-Calvet· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersMicrobiology

A. San Millan

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4 papers

Recent·Most cited

The distribution of fitness effects of plasmid pOXA-48 in clinical enterobacteria

A. Fernandez-Calvet, L. Toribio-Celestino, A. Alonso-del Valle, J. Sastre-Dominguez, P. Valdes-Chiara, A. San Millan, J. DelaFuente

This study investigates the fitness effects of the plasmid pOXA-48 in clinical enterobacteria using CRISPR-Cas9 to cure plasmids, revealing mostly neutral effects with rare fitness costs or benefits.

bioRxiv · Jul 11, 2023 · PreprintMicrobiology

Antimicrobial resistance level and conjugation permissiveness shape plasmid distribution in clinical enterobacteria

A. Alonso-del Valle, L. Toribio-Celestino, A. Quirant, C. Tardio Pi, J. DelaFuente, R. Canton, E. Rocha, C. Ubeda, R. Pena-Miller, A. San Millan

The paper investigates how antimicrobial resistance levels and conjugation permissiveness influence plasmid distribution in clinical enterobacteria, showing that specific bacterial clones stabilize plasmid spread.

bioRxiv · Apr 3, 2023Microbiology

The distribution of plasmid fitness effects explains plasmid persistence in bacterial communities

A. Alonso-del Valle, R. Leon-Sampedro, J. Rodriguez-Beltran, J. DelaFuente, M. Hernandez-Garcia, P. Ruiz-Garbajosa, R. Canton, R. Pena-Miller, A. San Millan

The study determines the distribution of fitness effects for plasmid pOXA-48 in gut bacteria, showing quasi-neutral effects and beneficial effects in some isolates, and links plasmid persistence to bacterial diversity and phylogeny.

bioRxiv · Aug 1, 2020 · PreprintMicrobiology

Collateral Sensitivity Associated with Antibiotic Resistance Plasmids

C. Herencias, J. Rodriguez-Beltran, R. Leon-Sampedro, A. Alonso-del Valle, J. Palkovicova, R. Canton, A. San Millan

This study investigates collateral sensitivity associated with antibiotic resistance plasmids, showing its conservation in clinical isolates and potential for selective elimination of plasmid-carrying bacteria.

bioRxiv · Jul 10, 2020Microbiology