A Diversity Outbred F1 mouse model identifies host-intrinsic genetic regulators of response to immune checkpoint inhibitors
J. B. HACKETT, J. E. Glassbrook, M. C. Muniz, M. Bross, A. Fielder, G. Dyson, J. McCasland, N. Movahhedin, C. E. McCarthy-Leo, H. M. Gibson
The paper identifies prolactin as a host-intrinsic genetic regulator of response to immune checkpoint inhibitors using Diversity Outbred and Collaborative Cross mouse models.
bioRxiv · Oct 7, 2021Immunology