Author

A. G. Heriot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. Behrenbruch· 2 shared C. Shembrey· 2 shared F. Hollande· 2 shared M. Foroutan· 2 shared A. Puisieux· 1 shared A.-M. Patch· 1 shared B. Cooper· 1 shared B. Knowles· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Behrenbruch

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A new highly-specific Natural Killer cell-specific gene signature predicting recurrence in colorectal cancer patients.

C. Shembrey, C. Behrenbruch, B. P. Loveday, A. G. Heriot, M. Foroutan, F. Hollande

This paper develops a CRC-specific NK cell gene signature that predicts recurrence in colorectal cancer patients by identifying high NK cell activity associated with improved survival.

bioRxiv · Apr 29, 2022Cancer Biology

Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer

C. Behrenbruch, M. Foroutan, P. Lind, J. Smith, M. Grandin, B. Cooper, C. Shembrey, S. Ramm, K. Cowley, I. Nikolic, J. Liuu, J. Cursons, R. Millen, A.-M. Patch, N. D. Huntington, , F. Hollande

This study identifies FOLFOX resistance in metastatic CRC through cell cycle checkpoint dysregulation and shows that targeting these checkpoints can resensitize resistant organoids to FOLFOX.

bioRxiv · Feb 4, 2021 · PreprintCancer Biology