Author

N. D. Huntington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Behrenbruch· 2 shared J. Cursons· 2 shared M. Foroutan· 2 shared A. G. Heriot· 1 shared A. J. Costello· 1 shared A. Kallies· 1 shared A. P. Ng· 1 shared A. Pfefferle· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

C. Behrenbruch

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 4, 2021

Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer

C. Behrenbruch, M. Foroutan, P. Lind…·F. Hollande

This study identifies FOLFOX resistance in metastatic CRC through cell cycle checkpoint dysregulation and shows that targeting these checkpoints can resensitize resistant organoids to FOLFOX.

DOI 10.1101/2021.02.04.429849

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivDec 19, 2020

The ratio of exhausted to resident infiltrating lymphocytes is prognostic for colorectal cancer patient outcome

M. Foroutan, R. Molania, A. Pfefferle…·N. D. Huntington

This study identifies signatures of lymphocyte residency and exhaustion in colorectal cancer using single-cell RNA-seq and shows their association with patient survival outcomes.

DOI 10.1158/2326-6066.cir-21-0137

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 28, 2020

The clonal and molecular aetiology of emergency dendritic cell development

D. S. Lin, L. Tian, S. Tomei…·S. H. Naik

This study investigates Flt3L-driven emergency dendritic cell development, revealing clonal expansion and molecular mechanisms in HSPCs leading to cDC1 generation.

DOI 10.1101/2020.05.28.120188

mousescRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 16, 2020

Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression

S. Mangiola, P. McCoy, M. Modrak…·C. M. Hovens

This study uses transcriptome sequencing and multiplex imaging to show that monocytic cells drive prostate cancer progression and immune modulation.

DOI 10.1101/2020.03.16.993162

humanbulk RNA-seq

𝕏 PostBluesky