Author

A. G. Shuparski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:scRNA-seq· 4 Organism:mouse· 3 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. W. Higgins· 4 shared L. J. McHeyzer-Williams· 4 shared M. G. McHeyzer-Williams· 4 shared K. B. Miller· 3 shared A. M. Robinson· 2 shared C. R. Dufaud· 1 shared

Activity by Year

2021-2021 · peak 4/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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4 shared papersImmunology

B. W. Higgins

Mutual co-authors in cluster

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 27, 2021

PD-1 checkpoint blockade activates germinal center follicular T cell programs that disrupt type 2 isotype-specific antibody homeostasis

A. G. Shuparski, B. W. Higgins, K. B. Miller…·M. G. McHeyzer-Williams

Acute PD-1 blockade disrupts type 2 isotype-specific antibody homeostasis by amplifying TFH2 programs and altering GC B cell dynamics.

DOI 10.1101/2021.09.27.462076

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 17, 2021

Evolution of antigen-specific follicular helper T cell transcriptional programs across effector function and through to memory

A. M. Robinson, B. W. Higgins, A. G. Shuparski…·M. G. McHeyzer-Williams

This study identifies antigen-specific transcriptional programs in follicular helper T cells across effector function and memory development, revealing distinct inflammatory and anti-inflammatory modules.

DOI 10.1101/2021.09.17.460841

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 31, 2021

Programming isotype specific plasma cell differentiation

B. W. Higgins, A. G. Shuparski, K. B. Miller…·M. G. McHeyzer-Williams

This study identifies isotype-specific molecular programs in murine plasma cells, revealing distinct pathways for IgM, IgG1, IgG2a/b, and IgA that govern antigen clearance and immune protection.

DOI 10.1101/2021.08.31.458458

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 10, 2021

PD-1 checkpoint blockade disrupts CD4 T cell regulated adaptive B cell tolerance to foreign antigens

C. R. Dufaud, A. G. Shuparski, B. W. Higgins…·M. G. McHeyzer-Williams

The paper shows PD-1 blockade disrupts CD4 T cell regulation of B cell tolerance, leading to increased IgG1 plasma cell differentiation and anti-commensal antibody production.

DOI 10.1101/2021.06.10.447979

𝕏 PostBluesky