Author

A. Garza-Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Agapova· 1 shared A. Cheyne· 1 shared A. O'Garra· 1 shared C. D. Sohaskey· 1 shared D. B. Young· 1 shared D. M. Hunt· 1 shared G. Larrouy-Maumus· 1 shared K. Nunta· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. Agapova

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3 papers

Recent·Most cited

Modulation of the cAMP levels with a conserved actinobacteria phosphodiesterase enzyme reduces antimicrobial tolerance in mycobacteria

M. Thomson, K. Nunta, A. Cheyne, Y. Liu, A. Garza-Garcia, G. Larrouy-Maumus

This study identifies a phosphodiesterase enzyme that reduces cAMP levels in mycobacteria, increasing antimicrobial susceptibility and revealing a new target for antimicrobial development.

bioRxiv · Aug 26, 2020 · PreprintMicrobiology

Transcriptomic characterization of tuberculous sputum reveals a host Warburg effect and microbial cholesterol catabolism

R. P. Lai, T. Cortes, S. Marais, N. Rockwood, M. L. Burke, A. Garza-Garcia, S. Horswell, A. O'Garra, D. B. Young, R. J. Wilkinson

This study uses RNA-sequencing on TB sputum to reveal host metabolic shifts and microbial cholesterol catabolism during tuberculosis transmission.

bioRxiv · Mar 9, 2020Microbiology

Nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis

A. Agapova, D. M. Hunt, M. Petridis, A. Garza-Garcia, C. D. Sohaskey, L. P. Carvalho

This study investigates how Mycobacterium tuberculosis uses amino acids as nitrogen sources, revealing key metabolic properties and the role of alanine dehydrogenase in nitrogen assimilation.

bioRxiv · Aug 5, 2018Microbiology