A. Goriely

Two for tau: Automated model discovery reveals two-stage tau aggregation dynamics in Alzheimer's disease

This paper uses neural networks to discover two-stage tau aggregation dynamics from PET data, revealing a more accurate model than traditional reaction-diffusion approaches.

Multilevel irreversibility reveals higher-order organisation of non-equilibrium interactions in human brain dynamics

This paper introduces a framework to quantify irreversibility in brain network dynamics across multiple levels and identifies higher-order organizational patterns in human brain interactions.

Human spermatogonial stem cells retain states with a foetal-like signature

This study identifies a foetal-like state 0B in human spermatogonial stem cells that maintains a suppressive transcriptomic program, contrasting with rodent models where this state is not maintained into adulthood.

Mechanics reveals the role of peristome geometry in prey capture in carnivorous pitcher plants (Nepenthes)

This study uses mechanics to explore how peristome geometry in Nepenthes pitcher plants influences prey capture, finding that shape and size correlate with capture efficiency and evolutionary adaptation.

A simple Turing reaction-diffusion model can explain how mother centrioles break symmetry to generate a single daughter

The paper proposes a Turing reaction-diffusion model to explain how PLK4 breaks symmetry to generate a single daughter centriole.

Front propagation and arrival times in networks with application to neurodegenerative diseases

The paper develops and compares three methods to estimate arrival times in network dynamics, applied to toxic protein propagation in neurodegenerative diseases.

Mother centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly

Predicting brain atrophy from tau pathology: A summary of clinical findings and their translation into personalized models

The paper develops personalized tau-atrophy models using clinical data to estimate brain atrophy rates linked to tau pathology in Alzheimer's disease.

Multiscale integration of environmental stimuli in plant tropism produces complex behaviors

The paper models multiscale plant tropism by linking hormone transport to tissue deformation, showing how multiple stimuli lead to complex growth behaviors.