S.-S. Wong

Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes

The paper shows that Spd-2 recruits Polo and Aurora A to form two distinct scaffolds, Cnn-scaffold and TACC-scaffold, which are essential for mitotic centrosome assembly in Drosophila.

A hemagglutinin and neuraminidase biased immunological memory shapes the dynamics of antibody responses to Influenza A virus

The paper shows that pre-existing immunity to specific influenza antigens biases post-infection antibody responses, altering their dynamics and breadth.

Cdk/Cyclin activity helps set mitotic centrosome size by influencing the centrosome growth rate and growth period

The paper shows that Cdk/Cyclin activity regulates mitotic centrosome size by modulating growth rate and period in Drosophila embryos.

Integrated Drivers of Basal and Acute Immunity in Diverse Human Populations

The paper examines factors influencing immunity across diverse populations, finding ancestry and age significantly affect immune responses and disease severity.

The episodic resurgence of highly pathogenic avian influenza H5 virus

This study tracks the resurgence of H5N1 avian influenza, identifying key events and genetic changes that contributed to its global spread from 2016/17 to 2021/22.

Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal-end

The paper shows that CP110 and Cep97 at the distal end of centrioles influence cartwheel growth at the proximal end through interactions with Plk4 oscillations.

Centriole growth is not limited by a finite pool of components, but is limited by the Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL

The paper shows that centriole growth in Drosophila embryos is not limited by component availability but by Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL, which regulates growth timing.

Mother centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly