Cell BiologybioRxivPreprint
The glycolysis regulator PFKFB4 interacts with ICMT and activates RAS/AKT signaling-dependent cell migration in melanoma.
M. Sittewelle, V. Kappes, D. Lecuyer, A. H. Monsoro-Burq
This study identifies a novel glycolysis-independent role of PFKFB4 in promoting melanoma cell migration through interaction with ICMT and activation of RAS/AKT signaling.
DOI 10.1101/2020.03.23.004119