Site-specific acetylation of polynucleotide kinase 3-phosphatase (PNKP) regulates its distinct role in DNA repair pathways
A. Islam, A. Chakraborty, A. H. Sarker, U. K. Aryal, G. Sharma, I. Boldogh, T. Hazra
This study shows that acetylation of PNKP at K142 and K226 regulates its distinct roles in DNA repair pathways, with K142 involved in BER/SSBR and K226 in DSBR.
bioRxiv · Jun 21, 2023Biochemistry