Author

U. K. Aryal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Chakraborty· 1 shared A. E. Salyer· 1 shared A. H. Sarker· 1 shared A. Islam· 1 shared A. T. Specht· 1 shared C. D'Souza-Schorey· 1 shared E. K. LaVigne· 1 shared E. N. Howe· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. Chakraborty

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Site-specific acetylation of polynucleotide kinase 3-phosphatase (PNKP) regulates its distinct role in DNA repair pathways

A. Islam, A. Chakraborty, A. H. Sarker, U. K. Aryal, G. Sharma, I. Boldogh, T. Hazra

This study shows that acetylation of PNKP at K142 and K226 regulates its distinct roles in DNA repair pathways, with K142 involved in BER/SSBR and K226 in DSBR.

bioRxiv · Jun 21, 2023Biochemistry

RyR2/IRBIT regulates insulin gene transcription, insulin content, and secretion in the insulinoma cell line INS-1

K. E. Harvey, E. K. LaVigne, M. S. Dar, E. P. S. Pratt, A. E. Salyer, P. A. Sample, U. K. Aryal, H. Gowher, G. H. Hockerman

Deletion of RyR2 or IRBIT in INS-1 cells reduces insulin content and secretion, with RyR2 also decreasing IRBIT levels and affecting DNA methylation and proteome regulation.

bioRxiv · Nov 24, 2021Cell Biology

Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth

E. N. Howe, M. D. Burnette, M. E. Justice, J. W. Clancy, I. H. Guldner, P. M. Schnepp, V. Hendrick, U. K. Aryal, A. T. Specht, J. Li, C. D'Souza-Schorey, J. J. Zartman, S. Zhang

This study identifies Rab11b as a mediator of breast cancer brain metastasis by promoting integrin recycling and mechanotransduction.

bioRxiv · Jun 11, 2019Cancer Biology