Author

T. Hazra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. CHAKRABORTY· 3 shared A. Ali· 1 shared A. H. Sarker· 1 shared A. Islam· 1 shared A. Sahan· 1 shared A. Sharma· 1 shared B. Krishnan· 1 shared D. Sahoo· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

A. CHAKRABORTY

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntingtons disease

A. CHAKRABORTY, S. G. Sreenivasmurthy, W. Miller, W. Huai, T. Biswas, S. M. Mandal, L. Bosca, B. Krishnan, G. Ghosh, T. Hazra

This study shows that F2,6BP restores PNKP activity and alleviates neurodegenerative symptoms in HD and SCA3 by rescuing DNA repair and genome integrity.

bioRxiv · Oct 26, 2023Biochemistry

Site-specific acetylation of polynucleotide kinase 3-phosphatase (PNKP) regulates its distinct role in DNA repair pathways

A. Islam, A. Chakraborty, A. H. Sarker, U. K. Aryal, G. Sharma, I. Boldogh, T. Hazra

This study shows that acetylation of PNKP at K142 and K226 regulates its distinct roles in DNA repair pathways, with K142 involved in BER/SSBR and K226 in DSBR.

bioRxiv · Jun 21, 2023Biochemistry

DNA glycosylase NEIL2 prevents Fusobacterium-mediated inflammation and DNA damage in colonic epithelial cells

I. Sayed, A. Chakraborty, A. Ali, A. Sharma, A. Sahan, D. Sahoo, P. Ghosh, T. Hazra, S. Das

This study shows that NEIL2, a DNA repair enzyme, is downregulated by Fusobacterium infection, leading to DNA damage and inflammation in colonic epithelial cells, and this effect is specific to microsatellite stable colorectal cancers.

bioRxiv · Jun 11, 2020Immunology