Iron regulatory proteins 1 and 2 have opposing roles in regulating inflammation in bacterial orchitis
N. Ghatpande, A. Harrer, B. Azoulay, N. Guttmann-Raviv, S. Bhushan, A. Meinhardt, E. G. Meyron-Holtz
This study shows that IRP1 deletion reduces inflammation and testicular damage in UPEC-induced orchitis, while IRP2 deletion increases inflammation.
bioRxiv · Aug 16, 2023Immunology