Iron Regulatory Protein 1 is Required for the Propagation of Inflammation in Inflammatory Bowel Disease
L. Fahoum, S. Belizowsky, N. Ghatpande, N. Guttmann-Raviv, W. Zhang, L. Kuanyu, T. Wing-Hang, A. Nyska, M. Waterman, R. Weisshof, A. Zukirman, E. Meyron-Holtz
This study identifies IRP1 as a key driver of inflammation in IBD by linking iron homeostasis disruption to inflammatory propagation.
Journal of Biological Chemistry · Sep 1, 2024Peer-reviewedImmunology