SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis.
A. Ikenaka, Y. Kitagawa, M. Yoshida, C.-Y. Lin, A. Niwa, T. Nakahata, M. K. Saito
This study shows SMN regulates mitochondrial metabolic maturation during myogenesis by controlling the MYOD-miRNA axis, with miR-1 and miR-206 supplementation restoring mitochondrial function in SMN-deficient cells.
bioRxiv · Feb 13, 2022Cell Biology