Author

T. Nakahata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. Niwa· 3 shared M. K. Saito· 2 shared Y. Zhang· 2 shared Y. Zhou· 2 shared A. Ikenaka· 1 shared A. Li· 1 shared A. Ohta· 1 shared B. Mao· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCell Biology

A. Niwa

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis.

A. Ikenaka, Y. Kitagawa, M. Yoshida, C.-Y. Lin, A. Niwa, T. Nakahata, M. K. Saito

This study shows SMN regulates mitochondrial metabolic maturation during myogenesis by controlling the MYOD-miRNA axis, with miR-1 and miR-206 supplementation restoring mitochondrial function in SMN-deficient cells.

bioRxiv · Feb 13, 2022Cell Biology

Inhibition of aryl hydrocarbon receptor signaling promotes the terminal differentiation of human erythrocytes

Y. Chen, Y. Dong, X. Lu, W. Li, Y. Zhang, B. Mao, X. Pan, X. Li, Y. Zhou, Q. An, F. Xie, S. Wang, Y. Xue, X. Cai, M. Lai, , F. Ma

This study shows that inhibiting AHR signaling enhances terminal differentiation of human erythrocytes by promoting F-actin remodeling and cytoskeleton maturation.

bioRxiv · Jun 8, 2021 · PreprintCell Biology

High-throughput Screening with Pluripotent Stem Cells Identifies CUDC-907 as an Effective Compound for Restoring the Proinflammatory Phenotype of Nakajo-Nishimura Syndrome

N. Kase, M. Terashima, A. Ohta, A. Niwa, F. Honda-Ozaki, Y. Kawasaki, T. Nakahata, N. Kanazawa, M. Saito

This study uses a pluripotent stem cell-derived model of Nakajo-Nishimura syndrome to identify CUDC-907 as a compound that reduces inflammatory chemokine overproduction.

bioRxiv · Jun 1, 2020Immunology

Biomimetic Aorta-Gonad-Mesonephros on-a-Chip to Study Human Developmental Hematopoiesis

R. Sugimura, R. Ohta, C. Mori, A. Li, T. Mano, E. Sano, K. Kosugi, T. Nakahata, A. Niwa, M. K. Saito, Y.-s. Torisawa

The paper develops a microfluidic AGM-on-a-chip to study human developmental hematopoiesis and demonstrates its ability to induce endothelial-to-hematopoietic transition.

bioRxiv · Dec 23, 2019Bioengineering

Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations

J. Li, Y. Fukase, Y. Shang, W. Zou, J. Munoz-Felix, L. Buitrago, J. van Agthoven, Y. Zhang, R. Hara, Y. Tanaka, R. Okamoto, T. Yasui, T. Nakahata, T. Imaeda, K. Aso, , B. S. Coller

This paper designs and evaluates two small-molecule Vβ3 antagonists that inhibit cell adhesion and bone resorption without inducing receptor conformational changes or enhancing angiogenesis at low concentrations.

bioRxiv · May 24, 2019Pharmacology & Toxicology