Author

A. J. Kooistra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Chemparathy· 1 shared A. Christopoulos· 1 shared A. Glukhova· 1 shared A. J. Venkatakrishnan· 1 shared A. K. Ma· 1 shared B. K. Kobilka· 1 shared C. J. Langmead· 1 shared C. R. Underwood· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

A. Chemparathy

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Author profile →

2 papers

Recent·Most cited

Differential GLP-1R binding and activation by peptide and non-peptide agonists

X. Zhang, M. J. Belousoff, P. Zhao, A. J. Kooistra, T. T. Truong, S. Y. Ang, C. R. Underwood, T. Egebjerg, P. Senel, G. D. Stewart, Y.-L. Liang, A. Glukhova, H. Venugopal, A. Christopoulos, S. G. Furness, , D. Wootten

The paper compares the binding and activation of the GLP-1 receptor by peptide and non-peptide agonists, revealing structural and functional differences that inform drug design.

bioRxiv · Aug 16, 2020Pharmacology & Toxicology

Uncovering patterns of atomic interactions in static and dynamic structures of proteins

A. J. Venkatakrishnan, R. Fonseca, A. K. Ma, S. A. Hollingsworth, A. Chemparathy, D. Hilger, A. J. Kooistra, R. Ahmari, M. M. Babu, B. K. Kobilka, R. Dror

The paper develops tools for analyzing interatomic interactions in protein structures and simulations, creating a web resource to identify functional interaction patterns in GPCRs, G proteins, kinases, and muscarinic receptors.

bioRxiv · Nov 13, 2019 · PreprintBiophysics