Author

A. J. Vernall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. E. Ussher· 3 shared R. F. Hannaway· 3 shared R. Lamichhane· 3 shared S. M. de la Harpe· 3 shared J. D. Tyndall· 2 shared M. Schneider· 2 shared F. Munro· 1 shared H. Galvin· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersImmunology

J. E. Ussher

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3 papers

Recent·Most cited

Neutrophils Suppress Mucosal-Associated Invariant T Cells

M. Schneider, R. F. Hannaway, R. Lamichhane, S. M. de la Harpe, J. D. Tyndall, A. J. Vernall, T. Kettle, J. E. Ussher

This study shows neutrophils suppress MAIT cell activation via cell-contact and H2O2, while activated MAIT cells induce neutrophil death through TNF, revealing a bidirectional regulatory feedback loop.

bioRxiv · Aug 28, 2019 · PreprintImmunology

Type I interferons are important co-stimulatory signals during T cell receptor mediated MAIT cell activation

R. Lamichhane, H. Galvin, R. F. Hannaway, S. M. de la Harpe, F. Munro, J. D. Tyndall, A. J. Vernall, J. L. McCall, M. Husain, J. E. Ussher

This study shows that type I interferons enhance TCR-mediated MAIT cell activation by boosting cytokine and granzyme B production.

bioRxiv · Jul 2, 2019Immunology

Transcriptional analysis defines TCR and cytokine-stimulated MAIT cells as rapid polyfunctional effector T cells that can coordinate the immune response

R. Lamichhane, M. Schneider, S. M. de la Harpe, T. W. R. Harrop, R. F. Hannaway, P. Dearden, J. R. Kirman, J. D. A. Tyndall, A. J. Vernall, J. E. Ussher

This study compares the transcriptional and effector responses of human MAIT cells to TCR and cytokine stimulation, revealing distinct functional outcomes.

bioRxiv · Apr 5, 2019 · PreprintImmunology