A. k. Pasupulati

ZEB2 transduces HIF1α dependent regulation of Transglutaminase 2 in glomerular podocytes

This study shows HIF1 stabilization increases ZEB2 and TRPC6, which enhance TG2 expression and activity, leading to glomerular injury.

Growth hormone induces mitotic catastrophe of podocytes and contributes toproteinuria

This study shows that growth hormone induces TGF-β1 signaling and causes mitotic catastrophe in podocytes, leading to proteinuria in diabetic nephropathy.

Molecular Evolution of Podocyte Slit-diaphragm Proteins

This study analyzes the evolutionary distribution and conservation of slit-diaphragm proteins across vertebrates and invertebrates, revealing conserved domains and the importance of intrinsically unstructured regions.

Structural Features and Oligomeric Nature of Human Podocin Domain

This study investigates the oligomeric structure of a truncated podocin domain, showing it primarily forms a 16mer with significant secondary structure and moderate tertiary packing.

Cerebral ischemia induces TRPC6 in the glomerular podocytes: A novel role for HIF1α/ZEB2 axis in the pathogenesis of stroke-induced proteinuria

This study identifies the HIF1α/ZEB2 axis as a novel mechanism inducing TRPC6 and causing podocyte dysfunction and proteinuria during cerebral ischemia.