Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms
A. K. Pal, D. Ghorai, X. Ge, B. Sarkar, A. K. Sahu, V. Chaudhary, S. Sanyal, M. Singh, A. Ghosh
This study shows that c-di-AMP modulates antibiotic sensitivity in M. smegmatis by interacting with protein effectors or mRNA 5-UTR regions, leading to differential drug resistance.
bioRxiv · Jul 5, 2023 · PreprintMicrobiology