Author

A. Chande

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Kumar· 3 shared N. Vijay· 3 shared A. Singh· 2 shared P. Ramdas· 2 shared R. Dalavi· 2 shared T. Mishra· 2 shared V. Bhardwaj· 2 shared A. Aggarwal· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

A. Kumar

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

HIV-1 Vpr induces ciTRAN to prevent transcriptional silencing of the provirus

V. Bhardwaj, A. Singh, R. Dalavi, L. Ralte, R. L. Chawngthu, N. Senthil Kumar, N. Vijay, A. Chande

This study identifies ciTRAN, a circular RNA induced by HIV-1 Vpr that sequesters SRSF1 to enhance viral transcription.

bioRxiv · Nov 4, 2022Microbiology

B.1.617.3 SARS CoV-2 spike E156G/Δ157-158 mutations contribute to reduced neutralization sensitivity and increased infectivity

T. Mishra, G. Joshi, A. Kumar, R. Dalavi, P. Pandey, S. Shukla, R. K. Mishra, A. Chande

This study identifies spike mutations in B.1.617.3 SARS-CoV-2 variants that reduce neutralization sensitivity and increase infectivity.

bioRxiv · Oct 4, 2021 · PreprintMicrobiology

SARS CoV-2 nucleoprotein enhances the infectivity of lentiviral spike particles

T. Mishra, S. M, P. Ramdas, A. K. Sahu, A. Kumar, A. Chande

This study identifies SARS CoV-2 nucleoprotein as an enhancer of spike-pseudotyped lentiviral particle infectivity without increasing sensitivity to RBD-based neutralization.

bioRxiv · Feb 11, 2021Microbiology

Integrated role of microRNA-30e-5p through targeting negative regulators of innate immune pathways during HBV infection and SLE

R. Mishra, S. Bhattacharya, B. S. Rawat, A. Kumar, A. Kumar, K. Niraj, A. Chande, P. Gandhi, D. Khetan, A. Aggarwal, S. Sato, P. Tailor, A. T. Takaoka, H. Kumar

This study identifies miR-30e as a master regulator of innate immune responses during HBV infection and SLE, showing its role in modulating immune pathways and therapeutic potential.

bioRxiv · Feb 29, 2020Immunology

Coevolution of retroviruses with SERINCs following whole-genome duplication divergence

P. Ramdas, V. Bhardwaj, A. Singh, N. Vijay, A. Chande

This study investigates the coevolution of retroviruses with SERINC proteins, showing functional conservation among SERINC paralogs and the role of whole-genome duplication in shaping anti-retroviral activity.

bioRxiv · Feb 24, 2020 · PreprintMicrobiology

A hypothetical new role for single-stranded DNA binding proteins in the immune system

N. Vijay, A. Chande

The paper hypothesizes that SSB proteins may act as ssDNA sensors in the immune system and identifies potential candidate genes, including HMGB1, for further investigation.

bioRxiv · May 11, 2018Immunology