Author

A. K. Tharkeshwar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

S. M. Ferguson· 2 shared G. S. Shadel· 1 shared G. Talaia· 1 shared J. Amick· 1 shared P. De Camilli· 1 shared W. F. Hancock-Cerutti· 1 shared Z. Wu· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

S. M. Ferguson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

W. F. Hancock-Cerutti, Z. Wu, A. K. Tharkeshwar, S. M. Ferguson, G. S. Shadel, P. De Camilli

The paper shows that VPS13C deficiency leads to lysosomal lipid changes and activates the cGAS/STING pathway via mtDNA accumulation and impaired STING degradation.

bioRxiv · Jun 8, 2021Cell Biology

PQLC2 signals lysosomal cationic amino acid abundance to the C9orf72 complex

J. Amick, A. K. Tharkeshwar, G. Talaia, S. M. Ferguson

The paper identifies PQLC2 as a lysosomal cationic amino acid transporter that interacts with the C9orf72 complex and regulates its recruitment based on amino acid availability.

bioRxiv · Jun 13, 2019Cell Biology