Hyperactivation of L-lactate oxidase by liquid-liquid phase separation
T. Ura, A. Kagawa, H. Yagi, N. Tochio, T. Kigawa, T. Mikawa, K. Shiraki
This study shows that L-lactate oxidase forms liquid droplets that enhance enzyme activity by reducing KM and increasing kcat, representing the first report of increased kcat through droplet formation.
Scientific Reports · Jan 25, 2023Peer-reviewedBiochemistry