Author

N. Tochio

RIKEN Center for Integrative Medical SciencesORCID 0000-0002-9107-2274Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 1

Frequent Co-Authors

T. KigawaiD· 2 shared A. Kagawa· 1 shared H. Yagi· 1 shared K. Shiraki· 1 shared T. Mikawa· 1 shared T. Ura· 1 shared Taiichi SakamotoiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

T. KigawaORCID

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2 papers

Recent·Most cited

Expanding the Frontiers of Structural Analysis in Short RNAs by Ultra-High Field 1.3 GHz NMR

N. Tochio, Taiichi Sakamoto, T. Kigawa

This paper demonstrates the first media-free detection of field-induced RDCs in a short RNA using 1.3 GHz NMR, showing structural insights and unique chemical shift anisotropy effects.

bioRxiv · Aug 24, 2026 · PreprintBiophysics

Hyperactivation of L-lactate oxidase by liquid-liquid phase separation

T. Ura, A. Kagawa, H. Yagi, N. Tochio, T. Kigawa, T. Mikawa, K. Shiraki

This study shows that L-lactate oxidase forms liquid droplets that enhance enzyme activity by reducing KM and increasing kcat, representing the first report of increased kcat through droplet formation.

Scientific Reports · Jan 25, 2023Peer-reviewedBiochemistry