T. Kigawa

This paper demonstrates the first media-free detection of field-induced RDCs in a short RNA using 1.3 GHz NMR, showing structural insights and unique chemical shift anisotropy effects.

The paper develops an adaptive optimization system for NMR CEST experiments to improve estimation of minor protein conformational states using Bayesian methods and MCMC.

This study shows that L-lactate oxidase forms liquid droplets that enhance enzyme activity by reducing KM and increasing kcat, representing the first report of increased kcat through droplet formation.

The paper develops an NMR method to determine multi-state structures of proteins and applies it to yeast ubiquitin hydrolase 1, revealing dynamic motions critical for ubiquitin recognition and proteolysis.