ELQ-331 as a prototype for extremely durable chemoprotection against malaria
M. J. Smilkstein, S. Pou, A. Krollenbrock, L. A. Bleyle, R. A. Dodean, L. Frueh, D. J. Hinrichs, Y. Li, T. Martinson, M. Y. Munar, R. W. Winter, I. Bruzual, S. Whiteside, A. Nilsen, D. R. Koop, , M. K. Riscoe
This paper evaluates ELQ-331 as a long-acting injectable chemoprotective agent against malaria, showing it provides durable protection in mice for up to 4.5 months.
bioRxiv · Jul 2, 2019Pharmacology & Toxicology