Author

A. L. Moreira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Tsirigos· 3 shared A. H. Yeaton· 2 shared A. Herrera· 2 shared A. Rashidfarrokhi· 2 shared C. M. Rudin· 2 shared E. Bartnicki· 2 shared K. M. Khanna· 2 shared K.-K. Wong· 2 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Tsirigos

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Regulatory T cells and IFN-γ-producing Th1 cells play a critical role in the pathogenesis of Sjögren's Syndrome

Y.-H. Wang, W. Li, M. McDermott, G.-Y. Son, G. Maiti, F. Zhou, A. Y. Tao, D. Raphael, A. L. Moreira, B. Shen, M. Vaeth, B. Nadorp, S. Chakravarti, R. S. Lacruz, S. Feske

This study identifies Treg cells and IFN-γ-producing Th1 cells as key drivers of Sjögren's Syndrome pathogenesis using a mouse model and single-cell transcriptomics.

bioRxiv · Jan 23, 2024 · PreprintImmunology

Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth

A. Rashidfarrokhi, R. Pillai, Y. Hao, W. Wu, B. Karadal-Ferrena, S. G. dimitriadoy, M. Cross, A. H. Yeaton, S. Ming Huang, A. J. Bhutkar, A. Herrera, S. Rajalingam, M. Hayashi, K.-l. Huang, E. Bartnicki, , T. Papagiannakopoulos

This study identifies a LKB1-LIF signaling axis in tumors that promotes immune evasion by reprogramming myeloid cells, and shows that inhibiting LIF signaling reduces tumor growth.

bioRxiv · Jul 15, 2023 · PreprintCancer Biology

KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance

A. M. Zavitsanou, Y. Hao, W. L. Wu, E. Bartnicki, R. Pillai, T. Karakousi, A. Herrera, A. Karatza, A. Rashidfarrokhi, S. Solis, M. Ciampricotti, A. H. Yeaton, E. Ivanova, C. A. Wohlhieter, T. B. Buus, , S. B. Koralov

This study shows KEAP1 mutations in lung adenocarcinoma lead to immune evasion by reducing dendritic cell and T cell responses, contributing to immunotherapy resistance.

bioRxiv · Sep 24, 2021 · PreprintCancer Biology

Classification and Mutation Prediction from Non-Small Cell Lung Cancer Histopathology Images using Deep Learning

N. Coudray, A. L. Moreira, T. Sakellaropoulos, D. Fenyo, N. Razavian, A. Tsirigos

This study uses deep learning to classify lung cancer subtypes and predict gene mutations from histopathology images, achieving high accuracy and outperforming human pathologists.

bioRxiv · Oct 3, 2017Cancer Biology