Author

G.-Y. Son

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

D. I. Yule· 2 shared F. Zhou· 2 shared R. S. Lacruz· 2 shared S. Feske· 2 shared A. L. Moreira· 1 shared A. Wahl· 1 shared A. Y. Tao· 1 shared A. Zou· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

D. I. Yule

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Regulatory T cells and IFN-γ-producing Th1 cells play a critical role in the pathogenesis of Sjögren's Syndrome

Y.-H. Wang, W. Li, M. McDermott, G.-Y. Son, G. Maiti, F. Zhou, A. Y. Tao, D. Raphael, A. L. Moreira, B. Shen, M. Vaeth, B. Nadorp, S. Chakravarti, R. S. Lacruz, S. Feske

This study identifies Treg cells and IFN-γ-producing Th1 cells as key drivers of Sjögren's Syndrome pathogenesis using a mouse model and single-cell transcriptomics.

bioRxiv · Jan 23, 2024 · PreprintImmunology

Loss of STIM1 and STIM2 in salivary glands disrupts ANO1 function but does not induce Sjogren's disease

G.-Y. Son, A. Zou, A. Wahl, K. T. Huang, M. Vinu, S. Zorgit, F. Zhou, L. Wagner, Y. Idaghdour, D. I. Yule, S. Feske, R. S. Lacruz

This study shows that loss of STIM1 and STIM2 in salivary glands reduces ANO1 function and saliva production but does not cause Sjogren's disease, suggesting a link between SOCE and TLR8 signaling.

bioRxiv · Jan 8, 2024Physiology

Functional Communication between IP3R and STIM2 at sub-threshold stimuli is a critical checkpoint for initiation of SOCE

M. Ahmad, H. L. Ong, H. Saadi, G.-Y. Son, Z. Shokatian, L. E. Terry, M. Trebak, D. I. Yule, I. Ambudkar

This study identifies IP3R-mediated local [Ca2+]ER decreases as the driver of immobile STIM2 clusters at ER-PM junctions, marking a checkpoint for SOCE initiation under sub-threshold stimuli.

bioRxiv · Sep 24, 2021 · PreprintPhysiology