Author

A. L. Smythers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

L. M. Hicks· 3 shared B. B. Flinn· 2 shared D. R. Kolling· 2 shared H. M. O'Dell· 2 shared K. M. Joseph· 2 shared A. A. Iannetta· 1 shared A. Asnani· 1 shared A. J. Wommack· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersPhysiology

L. M. Hicks

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Fluorescence Shadow Imaging of Hypsibius exemplaris Reveals Morphological Differences Between Sucrose- and CaCl2-Induced Osmobiotes

B. B. Flinn, H. M. O'Dell, K. M. Joseph, A. L. Smythers, D. P. Neff, L. M. Hicks, M. L. Norton, D. R. Kolling

The paper develops a new shadow imaging method with confocal laser scanning microscopy to measure tardigrade volume and compare morphological differences between sucrose- and CaCl2-induced tuns.

Scientific Reports · May 23, 2024Peer-reviewedPhysiology

Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy

S. A. Khetarpal, H. Li, T. Vitale, J. Rhee, L. Grauvogel, C. Castro, M. J. Mittenbühler, N. E. Houstis, A. Vargas-Castillo, A. L. Smythers, J. Liu, C. Curtin, H.-G. Sprenger, K. A. Blackmore, A. Kuznetsov, , A. Rosenzweig

This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.

bioRxiv · Jan 30, 2024 · PreprintPhysiology

Chemobiosis reveals tardigrade tun formation is dependent on reversible cysteine oxidation

A. L. Smythers, K. M. Joseph, H. M. O'Dell, T. A. Clark, J. R. Crislip, B. B. Flinn, M. H. Daughtridge, E. R. Stair, S. N. Mubarek, H. C. Lewis, D. R. Kolling, L. M. Hicks

This study shows that tardigrade tun formation relies on reversible cysteine oxidation driven by reactive oxygen species, using chemobiosis as a mechanism.

bioRxiv · May 15, 2023Biochemistry

High throughput peptidomics elucidates immunoregulatory functions of plant thimet oligopeptidase-directed proteostasis

G. V. Popescu, S. C. Popescu, L. M. Hicks, A. J. Wommack, A. A. Iannetta, P. Berg, N. Nejat, A. L. Smythers, R. Setu, U. Wesser, A. L. Purvis, Z. A. Brown

The paper uses peptidomics to show that thimet oligopeptidases regulate immune responses by modulating redox homeostasis and phytocytokine production in Arabidopsis.

bioRxiv · May 11, 2022 · PreprintPlant Biology