Author

A. La Ferlita

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

E. Chavdoula· 3 shared L. Sehgal· 3 shared P. N. Tsichlis· 3 shared V. Anastas· 3 shared A. Orlacchio· 2 shared C. Tsatsanis· 2 shared G. I. Laliotis· 2 shared S. Alaimo· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

E. Chavdoula

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4 papers

Recent·Most cited

Cancer BiologybioRxivJul 7, 2023

Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

E. Chavdoula, V. Anastas, A. La Ferlita…·P. N. Tsichlis

This study identifies KDM2B's role in regulating amino acid metabolism through interactions with ncPRC1.1, MYC, and ATF4, revealing a metabolic network linked to poor prognosis in TNBC.

DOI 10.1016/j.metabol.2023.155719

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivDec 26, 2020

IWS1 phosphorylation by AKT3 controls nuclear export of type I IFN mRNAs and sensitivity to oncolytic viral infection, by regulating the alternative RNA splicing of U2AF2.

G. I. Laliotis, A. Kenney, E. Chavdoula…·P. N. Tsichlis

The paper was withdrawn due to concerns about the validity of the reported alternative splicing mechanism of U2AF2 and potential data manipulation.

DOI 10.1038/s42003-021-02668-z

experimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintAug 3, 2020

Divergent use of metabolic fluxes in breast cancer metastasis

D. Mathur, C. Liao, A. La Ferlita…·J. Xavier

This study identifies a strong Warburg effect in lung-homing breast cancer cells, characterized by high lactate secretion and a specific gene expression signature, which correlates with lung metastases.

DOI 10.1101/2020.08.03.234468

humanmetabolomics

𝕏 PostBluesky

Cancer BiologybioRxivJul 14, 2020

IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing.

G. I. Laliotis, E. Chavdoula, M. D. Paraskevopoulou…·P. N. Tsichlis

The paper was withdrawn due to concerns about the validity of the reported splicing mechanism and data integrity.

DOI 10.1038/s41467-021-24795-1

bulk RNA-seqexperimental assay

𝕏 PostBluesky