Author

A. Orlacchio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

V. Coppola· 3 shared A. La Ferlita· 2 shared C. Tsatsanis· 2 shared E. Chavdoula· 2 shared G. I. Laliotis· 2 shared L. Sehgal· 2 shared P. N. Tsichlis· 2 shared V. Anastas· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

V. Coppola

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IWS1 phosphorylation by AKT3 controls nuclear export of type I IFN mRNAs and sensitivity to oncolytic viral infection, by regulating the alternative RNA splicing of U2AF2.

G. I. Laliotis, A. Kenney, E. Chavdoula, A. Orlacchio, A. K. Kaba, A. La Ferlita, V. Anastas, C. Tsatsanis, J. D. Beane, L. Sehgal, V. Coppola, J. S. Yount, P. N. Tsichlis

The paper was withdrawn due to concerns about the validity of the reported alternative splicing mechanism of U2AF2 and potential data manipulation.

bioRxiv · Dec 26, 2020Cancer Biology

IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing.

G. I. Laliotis, E. Chavdoula, M. D. Paraskevopoulou, A. D. Kaba, A. La Ferlita, S. Singh, V. Anastas, S. Alaimo, A. Orlacchio, K. A. Nair, V. Taraslia, I. Vlachos, M. Capece, A. Hatzigeorgiou, D. I. Palmieri, , P. N. Tsichlis

The paper was withdrawn due to concerns about the validity of the reported splicing mechanism and data integrity.

bioRxiv · Jul 14, 2020Cancer Biology

Tagging allows faithful tracing of expression and enhances biochemical detection of Ran Binding Protein 9 in vivo and reveals its interaction with Nucleolin.

S. Soliman, A. E. Stark, M. Gardner, S. W. Harshman, C. C. Breece, F. Amari, A. Orlacchio, M. Chen, A. Tessari, J. A. Martin, R. Visone, M. A. Freitas, K. La Perle, D. Palmieri, V. COPPOLA

The paper generates a novel mouse strain with a tagged RanBP9 protein, enabling reliable detection and revealing its interaction with Nucleolin.

bioRxiv · Dec 3, 2019Bioengineering