Author

A. Lautwein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

B. Opgenoorth· 1 shared B. Sebastian· 1 shared C. Renz· 1 shared D. Buckert· 1 shared D. Müller-Enoch· 1 shared E. Belonovskaya· 1 shared E. Naruta· 1 shared G. Pongratz· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

B. Opgenoorth

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Author profile →

2 papers

Recent·Most cited

TLR9-activated B cells improve their regulatory function by endogenously produced catecholamines

N. Honke, T. Lowin, B. Opgenoorth, N. Shaabani, A. Lautwein, J. R. Teijaro, M. Schneider, G. Pongratz

This study shows that TLR9-activated B cells produce catecholamines, enhancing their regulatory function through adrenergic receptor activation and increased IL-10 and co-inhibitory ligand expression.

bioRxiv · May 24, 2020 · PreprintImmunology

ω-imidazolyl-alkyl derivatives as new preclinical drug candidates for NASH therapy

T. Diesinger, A. Lautwein, V. Buko, E. Belonovskaya, O. Lukivskaya, E. Naruta, S. Kirko, V. Andreev, R. Dvorsky, D. Buckert, B. Sebastian, C. Renz, D. Müller-Enoch, T. Wirth, T. Haehner

The paper tests two new CYP2E1 inhibitors, I-ol and I-an, in a rat model of NASH, finding they reduce pathological markers and show good tolerability.

bioRxiv · Jun 28, 2019 · PreprintPharmacology & Toxicology