Author

N. Honke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 1

Frequent Co-Authors

J. R. Teijaro· 2 shared N. Shaabani· 2 shared A. Lautwein· 1 shared B. Opgenoorth· 1 shared D. C. Lazar· 1 shared D.-E. Zhang· 1 shared G. Pongratz· 1 shared J. L. Johnson· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

J. R. Teijaro

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2 papers

Recent·Most cited

TLR9-activated B cells improve their regulatory function by endogenously produced catecholamines

N. Honke, T. Lowin, B. Opgenoorth, N. Shaabani, A. Lautwein, J. R. Teijaro, M. Schneider, G. Pongratz

This study shows that TLR9-activated B cells produce catecholamines, enhancing their regulatory function through adrenergic receptor activation and increased IL-10 and co-inhibitory ligand expression.

bioRxiv · May 24, 2020 · PreprintImmunology

ISG15 drives immune pathology and respiratory failure during viral infection

N. Shaabani, J. Zak, J. L. Johnson, Z. Huang, N. Nguyen, D. C. Lazar, V. F. Vartabedian, N. Honke, M. Prinz, K.-P. Knobeloch, K.-i. Arimoto, D.-E. Zhang, S. D. Catz, J. R. Teijaro

This study shows that lack of deISGylation during viral infection leads to immune pathology and respiratory failure, with extracellular ISG15 playing a key role in inflammation and disease severity.

bioRxiv · Apr 13, 2020 · PreprintImmunology