Author

A. Leopoldi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:organoid / primary culture· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

G. Jonsson· 2 shared A. Hagelkrueys· 1 shared A. Hagelkrüys· 1 shared A. Marco· 1 shared A. Mirazimi· 1 shared A. Pitaval· 1 shared A. Ullate-Agote· 1 shared A. Vilas-Zornoza· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

G. Jonsson

Mutual co-authors in cluster

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2 papers

Recent·Most cited

An automated microfluidic platform integrating functional vascularized organoids-on-chip

C. Quintard, G. Jonsson, C. Laporte, C. Bissardon, A. Pitaval, N. Werschler, A. Leopoldi, A. Hagelkrüys, P. Blandin, J.-L. Achard, F. Navarro, Y. Fouillet, J. M. Penninger, X. Gidrol

This paper develops a microfluidic platform to create functional vascular networks around organoids, demonstrating perfusion within spheroids and vascular organoids over 15 days.

Nature Communications · Feb 16, 2024Peer-reviewedBioengineering

A diabetic milieu increases cellular susceptibility to SARS-CoV-2 infections in engineered human kidney organoids and diabetic patients

E. Garreta, P. Prado, M. L. Stanifer, V. Monteil, C. Hurtado del Pozo, A. Ullate-Agote, A. Vilas-Zornoza, J. P. Romero, G. Jonsson, R. Oria, A. Leopoldi, A. Hagelkrueys, D. Moya-Rull, F. Gonzalez, A. Marco, , N. Montserrat

This study shows that a diabetic environment increases SARS-CoV-2 susceptibility in kidney organoids and patients by upregulating ACE2, which is critical for viral replication.

bioRxiv · Aug 13, 2021 · PreprintCell Biology