Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
G. Cannone, L. Berto, F. Malhaire, G. Ferguson, A. Fouillen, S. Balor, J. Font-Ingles, A. Llebaria, C. GOUDET, A. Kotecha, V. R. Kutti, G. Lebon
This study reports cryoEM structures of mGlu5 receptor with different PAMs, showing how PAM binding modulates receptor conformation and function.
bioRxiv · Nov 7, 2023Biochemistry
H. Ajieren, A. Fox, E. Biggs, G. Albors, A. Llebaria, P. Irazoqui
This paper designs a low-cost photomodulator for in vivo photoactivation of a mGluR5 inhibitor, demonstrating its effectiveness in reducing pain response in rats.
bioRxiv · Oct 7, 2023 · PreprintPharmacology & Toxicology
H. Hu, C. Serra, A. Llebaria, A. A. Antolin
This study identifies differential polypharmacology between rucaparib and its metabolite M324, showing distinct kinase inhibition profiles with potential clinical implications.
bioRxiv · Nov 22, 2022 · PreprintPharmacology & Toxicology
A. Duran-Corbera, M. Faria, Y. Ma, E. Prats, A. Dias, J. Catena, K. L. Martinez, D. Raldua, A. Llebaria, X. Rovira
This paper develops a photoswitchable ligand for β1-adrenoceptor that enables light-controlled cardiac rhythm management in zebrafish larvae.
Angewandte Chemie International Edition · Jun 9, 2022Peer-reviewedPharmacology & Toxicology
G. Somalo-Barranco, C. Serra, D. Lyons, H. Piggins, R. Jockers, A. Llebaria
The paper designs and validates a family of photo-activatable melatonin ligands to study receptor activation with high temporal resolution.
bioRxiv · May 5, 2022Pharmacology & Toxicology
S. Pittolo, H. Lee, A. Llado, S. Tosi, M. Bosch, L. Bardia, X. Gomez-Santacana, A. Llebaria, E. Soriano, J. Colombelli, K. E. Poskanzer, G. Perea, P. Gorostiza
This paper introduces two-photon pharmacology to reversibly silence mGlu5 receptors in intact brain tissue, enabling study of synaptic and signaling processes.
bioRxiv · Jan 10, 2019Pharmacology & Toxicology