Computational and biochemical analysis of type IV Pilus dynamics and stability
Y. Karami, A. Lopez Castilla, A. Ori, J.-L. Thomassin, B. Bardiaux, T. E. Malliavin, N. Izadi-Pruneyre, O. Francetic, M. Nilges
The paper uses molecular dynamics simulations and biochemical experiments to study T4P stability, identifying a calcium-binding site important for function and suggesting it as a drug target.
bioRxiv · Apr 14, 2021Biochemistry