Author

N. Izadi-Pruneyre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:structural biology· 4 Organism:bacteria (other)· 3 Research Focus:protein folding & dynamics· 3 Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 2 Organism:E. coli· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. Bardiaux· 5 shared M. Lejeune· 3 shared M. Nilges· 3 shared P. Delepelaire· 3 shared A. Mechaly· 2 shared O. Francetic· 2 shared A. Haouz· 1 shared A. Lopez Castilla· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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5 shared papersMicrobiology

B. Bardiaux

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Ton Motor Conformational Switch and Peptidoglycan Role in Bacterial Nutrient Uptake

M. Zinke, M. Lejeune, A. Mechaly, B. Bardiaux, I. Boneca, P. Delepelaire, N. Izadi-Pruneyre

The paper investigates the conformational switch of ExbD in the Ton system and its role in nutrient uptake, revealing the anchoring function of peptidoglycan and proposing a mechanistic model.

bioRxiv · Aug 11, 2023Microbiology

Bridges instead of boats? The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope core of phospholipid trafficking

C. BELOIN, K. P. Grasekamp, B. Beaud, N. Taib, B. Audrain, B. Bardiaux, Y. Rossez, N. IZADI-PRUNEYRE, M. Lejeune, X. Trivelli, Z. Chouit, Y. Guerardel, J.-M. GHIGO, S. Gribaldo

This study investigates GPL trafficking in Veillonella parvula, revealing a minimal Mla system that directly connects membranes without chaperones or outer membrane lipoproteins, suggesting an ancestral core of the Mla system.

bioRxiv · Jun 30, 2023 · PreprintMicrobiology

Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system

R. Dazzoni, Y. Li, A. Lopez-Castilla, S. Brier, A. Mechaly, F. Cordier, A. Haouz, M. Nilges, O. Francetic, B. Bardiaux, N. Izadi-Pruneyre

The paper determines the structure of the PulL-PulM heterodimer in the T2SS assembly platform and proposes a model for its dynamic role in pseudopilus polymerization.

bioRxiv · Jul 16, 2022Microbiology

Dynamic interplay between a TonB dependent heme transporter and a TonB protein in a membrane environment

K. Somboon, O. Melling, M. Lejeune, G. M.S. Pinheiro, A. Paquelin, B. Bardiaux, M. Nilges, P. Delepelaire, S. Khalid, N. Izadi-Pruneyre

The paper uses molecular dynamics simulations to study the interaction between a heme transporter and a TonB-like protein in E. coli, revealing dynamic interactions and validating them experimentally.

bioRxiv · Apr 21, 2021Biophysics

Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog

V. Biou, R. J. D. Adaixo, M. Chami, P.-D. Coureux, B. Laurent, V. Y. Ntsogo Enguene, G. Cardoso de Amorim, N. Izadi-Pruneyre, C. Malosse, J. Chamot-Rooke, H. Stahlberg, P. Delepelaire

The paper determines the cryo-EM structures of ExbBSm and ExbB-ExbDSm complex, identifies key residues for function and interaction with TonB/HasB, and reveals the role of ExbBSm extension in heme acquisition.

bioRxiv · Apr 21, 2021Microbiology

Computational and biochemical analysis of type IV Pilus dynamics and stability

Y. Karami, A. Lopez Castilla, A. Ori, J.-L. Thomassin, B. Bardiaux, T. E. Malliavin, N. Izadi-Pruneyre, O. Francetic, M. Nilges

The paper uses molecular dynamics simulations and biochemical experiments to study T4P stability, identifying a calcium-binding site important for function and suggesting it as a drug target.

bioRxiv · Apr 14, 2021Biochemistry