Author

B. Bardiaux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 3 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:protein folding & dynamics· 4 Approach:biophysical modeling· 3 Research Focus:cell signaling & trafficking· 3 Assay:structural biology· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

N. Izadi-Pruneyre· 5 shared M. Lejeune· 3 shared M. Nilges· 3 shared A. Mechaly· 2 shared O. Francetic· 2 shared P. Delepelaire· 2 shared A. Belyy· 1 shared A. Daskalov· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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5 shared papersMicrobiology

N. Izadi-Pruneyre

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Ton Motor Conformational Switch and Peptidoglycan Role in Bacterial Nutrient Uptake

M. Zinke, M. Lejeune, A. Mechaly, B. Bardiaux, I. Boneca, P. Delepelaire, N. Izadi-Pruneyre

The paper investigates the conformational switch of ExbD in the Ton system and its role in nutrient uptake, revealing the anchoring function of peptidoglycan and proposing a mechanistic model.

bioRxiv · Aug 11, 2023Microbiology

Bridges instead of boats? The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope core of phospholipid trafficking

C. BELOIN, K. P. Grasekamp, B. Beaud, N. Taib, B. Audrain, B. Bardiaux, Y. Rossez, N. IZADI-PRUNEYRE, M. Lejeune, X. Trivelli, Z. Chouit, Y. Guerardel, J.-M. GHIGO, S. Gribaldo

This study investigates GPL trafficking in Veillonella parvula, revealing a minimal Mla system that directly connects membranes without chaperones or outer membrane lipoproteins, suggesting an ancestral core of the Mla system.

bioRxiv · Jun 30, 2023 · PreprintMicrobiology

Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system

R. Dazzoni, Y. Li, A. Lopez-Castilla, S. Brier, A. Mechaly, F. Cordier, A. Haouz, M. Nilges, O. Francetic, B. Bardiaux, N. Izadi-Pruneyre

The paper determines the structure of the PulL-PulM heterodimer in the T2SS assembly platform and proposes a model for its dynamic role in pseudopilus polymerization.

bioRxiv · Jul 16, 2022Microbiology

Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin

A. Belyy, F. Lindemann, D. Roderer, J. Funk, B. Bardiaux, J. Protze, P. Bieling, H. Oschkinat, S. Raunser

This study reveals how TccC3 toxin modifies F-actin by ADP-ribosylating threonine-148, disrupting actin dynamics and causing cell death.

bioRxiv · May 6, 2022Biochemistry

Characterization of the interaction domains between the phosphoprotein and the nucleocapsid of human Metapneumovirus

H. Decool, B. Bardiaux, L. C. Ruano, O. Sperandio, J. Fix, I. Gutsche, C.-A. Richard, M. Bajorek, J.-F. Eleouet, M. Galloux

This paper identifies the specific domains of the HMPV phosphoprotein (P) and nucleocapsid (NNuc) that mediate their interaction, showing the C-terminal 6 residues of P and the N-terminal domain of N are critical.

bioRxiv · Jun 2, 2021Microbiology

Dynamic interplay between a TonB dependent heme transporter and a TonB protein in a membrane environment

K. Somboon, O. Melling, M. Lejeune, G. M.S. Pinheiro, A. Paquelin, B. Bardiaux, M. Nilges, P. Delepelaire, S. Khalid, N. Izadi-Pruneyre

The paper uses molecular dynamics simulations to study the interaction between a heme transporter and a TonB-like protein in E. coli, revealing dynamic interactions and validating them experimentally.

bioRxiv · Apr 21, 2021Biophysics

Computational and biochemical analysis of type IV Pilus dynamics and stability

Y. Karami, A. Lopez Castilla, A. Ori, J.-L. Thomassin, B. Bardiaux, T. E. Malliavin, N. Izadi-Pruneyre, O. Francetic, M. Nilges

The paper uses molecular dynamics simulations and biochemical experiments to study T4P stability, identifying a calcium-binding site important for function and suggesting it as a drug target.

bioRxiv · Apr 14, 2021Biochemistry

Structural and molecular basis of cross-seeding barriers in amyloids

A. Loquet, A. Daskalov, V. Coustou, N. El Mammeri, M. Berbon, L. Andreas, B. Bardiaux, J. Stanek, A. Noubhani, B. Kauffmann, J. Wall, G. Pintacuda, S. Saupe, B. Habenstein

This study identifies molecular determinants that prevent cross-seeding between structurally similar amyloids, revealing that side-chain positions, not just backbone structure, dictate prion specificity.

bioRxiv · Jul 6, 2020Biochemistry

Aβ(1-42) tetramer and octamer structures reveal edge pores as a mechanism for membrane damage

S. Ciudad, E. Puig, T. Botzanowski, M. Meigooni, A. S. Arango, J. Do, M. Mayzel, M. Bayoumi, S. Chaignepain, G. Maglia, S. Cianferani, V. Orekhov, E. Tajkhorshid, B. Bardiaux, N. Carulla

This paper determines the structures of Aβ(1-42) tetramers and octamers in membrane-mimicking environments and identifies a new mechanism of membrane disruption via hydrophilic edge pores.

bioRxiv · Sep 12, 2019Biophysics