Author

A. M. Akimzhanov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1

Frequent Co-Authors

D. Boehning· 3 shared R. Tewari· 2 shared Y. Fan· 2 shared A. Abdullahi· 1 shared A. Andersohn· 1 shared A. N. Marsden· 1 shared B. Shayahati· 1 shared D. F. Boehning· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

D. Boehning

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Author profile →

4 papers

Recent·Most cited

Dynamic S-acylation of STIM1 is required for store-operated Ca 2+ entry

G. Kodakandla, S. J. West, M. X. Zhu, Q. Wang, R. Tewari, A. M. Akimzhanov, D. F. Boehning

The paper shows that S-acylation of STIM1 is required for CRAC channel assembly and function during store-operated calcium entry.

bioRxiv · Feb 15, 2022 · PreprintCell Biology

Regulation of T cell receptor signaling by protein acyltransferase DHHC21

Y. Fan, B. Shayahati, R. Tewari, D. Boehning, A. M. Akimzhanov

This study identifies DHHC21 as a critical regulator of T cell receptor signaling through S-acylation, showing its role in T cell activation and differentiation.

bioRxiv · Feb 10, 2020Cell Biology

Aggregated and hyperstable damage-associated molecular patterns are released during ER stress to modulate immune function

A. Andersohn, I. Garcia, Y. Fan, M. C. Thompson, A. M. Akimzhanov, A. Abdullahi, M. G. Jeschke, D. Boehning

The paper shows chronic ER stress releases protease-resistant DAMPs that activate dendritic cells and drive persistent inflammation.

bioRxiv · May 29, 2019Cell Biology

The palmitoyl acyltransferase DHHC5 mediates beta-adrenergic signaling in the heart by targeting Gα proteins and G protein-coupled receptor kinase 2

J. J. Chen, A. N. Marsden, A. M. Akimzhanov, D. Boehning

This study shows that DHHC5 mediates beta-adrenergic signaling in the heart by palmitoylating Gα proteins and GRK2, essential for downstream functional responses.

bioRxiv · Jul 17, 2018Cell Biology