A. M. Borman

Comparative transcriptional analysis of Candida auris biofilms following farnesol and tyrosol treatment

This study compares the transcriptomic responses of Candida auris biofilms to farnesol and tyrosol treatments, identifying gene expression changes and molecular pathways affected.

Strain and temperature dependent aggregation of Candida auris is attenuated by inhibition of surface amyloid proteins

This study investigates strain and temperature-dependent aggregation in Candida auris, finding that amyloid protein inhibition reduces aggregation without affecting cell separation.

Landscape-scale exposure to multiazole-resistant Aspergillus fumigatus bioaerosols

UK-wide citizen science surveillance finds a ubiquitous exposure to aerosolized spores of a human fungal pathogen that have evolved cross-resistance to essential clinical antifungal drugs.

Synergistic interaction of caspofungin combined with posaconazole against FKS wild-type and mutant Candida auris planktonic cells and biofilms

This study evaluates the synergistic effect of caspofungin and posaconazole against Candida auris planktonic cells and biofilms, showing significant reductions in minimum inhibitory concentrations and confirming synergistic interactions through multiple assays.

Transcriptional profiling of the Candida auris response to exogenous farnesol exposure

This study investigates the effects of farnesol on C. auris by analyzing gene expression and growth changes, revealing its impact on metabolism, metal ion levels, and antifungal mechanisms.

In vitro and in vivo interaction of caspofungin with isavuconazole against Candida auris planktonic cells and biofilms

This study evaluates the in vitro and in vivo synergistic effects of caspofungin and isavuconazole against Candida auris planktonic cells and biofilms, showing significant reductions in minimum inhibitory concentrations and fungal burden in mice.