J. Rhodes

Optimal investments in private land conservation depend more on landholder preferences than climate change

This study shows that landholder preferences are more important than climate change for optimizing private land conservation investments in koala habitats in New South Wales.

Determining the microbial species content in tissue from Alzheimer's and Parkinson's Disease patients

This study develops a nanopore sequencing method to detect fungal DNA in brain tissue and CSF from Alzheimer's and Parkinson's Disease patients, revealing fungal presence in healthy and diseased samples.

Genomic epidemiology of European Aspergillus fumigatus causing COVID-19-associated pulmonary aspergillosis in Europe

This study analyzes the genomic epidemiology of Aspergillus fumigatus causing CAPA in Europe, finding no unique genetic background but a notable prevalence of azole-resistance alleles.

Oxamniquine Derivatives Overcome Praziquantel Treatment Limitations for Schistosomiasis

This paper identifies novel oxamniquine derivatives that overcome praziquantel limitations in treating schistosomiasis by killing all three Schistosoma species and resistant strains.

Landscape-scale exposure to multiazole-resistant Aspergillus fumigatus bioaerosols

UK-wide citizen science surveillance finds a ubiquitous exposure to aerosolized spores of a human fungal pathogen that have evolved cross-resistance to essential clinical antifungal drugs.

Exploring a novel genomic safe-haven site in the human pathogenic mould Aspergillus fumigatus.

The paper identifies a conserved genomic safe-haven locus in Aspergillus fumigatus for inserting genetic constructs without affecting phenotype.

Perception of a conserved family of plant signalling peptides by the receptor kinase HSL3

The paper identifies CTNIPs as a conserved family of plant signaling peptides and shows that HSL3 is their receptor, revealing an ancient signaling module involved in stress responses.

Prioritizing Management for Cumulative Impacts

This paper identifies leverage nodes in an impact network to prioritize environmental management for reducing risks to ecosystems and species.

Targeting effector pathways in RAC1P29S-driven malignant melanoma

This study investigates the efficacy of targeting effector pathways of RAC1P29S in melanoma, showing that PAK and SRF/MRTF inhibitors reduce tumor growth in vitro and in zebrafish models.

Elevated prevalence of azole resistant Aspergillus fumigatus in urban versus rural environments in the United Kingdom

The paper assesses azole-resistant Aspergillus fumigatus prevalence in urban vs. rural soils in the UK, finding higher resistance in urban areas with specific genetic alleles.

Scc2/Nipbl Hops Between Chromosomal Cohesin Rings After Loading

This study shows Scc2/Nipbl dynamically hops between chromosomal cohesin rings after loading, suggesting a post-loading function in DNA loop extrusion.

Cohesin Can Remain Associated With Chromosomes During DNA Replication

The paper investigates whether cohesin complexes from G1 phase remain associated with chromatin during DNA replication, finding that they persist in S phase when cohesin turnover is inhibited.

Architecture and dynamics of the jasmonic acid gene regulatory network

This study uses RNA-Seq time series analysis of Arabidopsis thaliana to detail the dynamics of the jasmonic acid gene regulatory network and identify key transcription factors involved in plant defense.

Simulations of CYP51A from Aspergillus fumigatus in a model bilayer provide insights into triazole drug resistance

This study simulates CYP51A from Aspergillus fumigatus in a lipid bilayer to investigate azole drug resistance mechanisms.