Author

A. M. Guggisberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. J. Jezewski· 2 shared A. R. Odom John· 2 shared A. Y. Gandhi· 1 shared D. M. Hodge· 1 shared L. K. McLellan· 1 shared N. Ghebremichael· 1 shared N. M. Kafai· 1 shared P. M. Frasse· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

A. J. Jezewski

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2 papers

Recent·Most cited

Cooperativity mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites

A. J. Jezewski, A. M. Guggisberg, D. M. Hodge, N. Ghebremichael, L. K. McLellan, A. R. Odom John

This study identifies GAPDH cooperativity as a key factor in FSM resistance and MEP pathway regulation in Plasmodium falciparum.

bioRxiv · Nov 5, 2021 · PreprintMicrobiology

Suppression of drug resistance reveals a genetic mechanism of metabolic plasticity in malaria parasites

A. M. Guggisberg, P. M. Frasse, A. J. Jezewski, N. M. Kafai, A. Y. Gandhi, S. J. Erlinger, A. R. Odom John

The paper identifies a genetic mechanism of metabolic plasticity in malaria parasites by uncovering HAD2 as a phosphatase regulating drug resistance and PFK9 as a suppressor of resistance.

bioRxiv · Jun 18, 2018Microbiology