Author

P. M. Frasse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. R. Odom John· 2 shared A. J. Jezewski· 1 shared A. M. Guggisberg· 1 shared A. Y. Gandhi· 1 shared D. E. Goldberg· 1 shared D. L. Jakeman· 1 shared E. Soleimani· 1 shared J. J. Miller· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. R. Odom John

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2 papers

Recent·Most cited

Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria parasites

P. M. Frasse, J. J. Miller, E. Soleimani, J.-S. Zhu, D. L. Jakeman, J. M. Jez, D. E. Goldberg, A. R. Odom John

This study characterizes HAD5, a phosphomannomutase essential for GPI anchor biosynthesis in malaria parasites, showing its role in parasite egress and reinvasion and identifying a specific inhibitor.

bioRxiv · Jul 3, 2021Microbiology

Suppression of drug resistance reveals a genetic mechanism of metabolic plasticity in malaria parasites

A. M. Guggisberg, P. M. Frasse, A. J. Jezewski, N. M. Kafai, A. Y. Gandhi, S. J. Erlinger, A. R. Odom John

The paper identifies a genetic mechanism of metabolic plasticity in malaria parasites by uncovering HAD2 as a phosphatase regulating drug resistance and PFK9 as a suppressor of resistance.

bioRxiv · Jun 18, 2018Microbiology