Author

A. M. Houghton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Heinemann· 1 shared A. Koehne· 1 shared A. Lueger· 1 shared A. Santiso· 1 shared A. Sarsembayeva· 1 shared B. Freie· 1 shared D. P. MacPherson· 1 shared E. Babaeva· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Heinemann

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2 papers

Recent·Most cited

Myeloperoxidase promotes a tumorigenic microenvironment in non-small cell lungcancer

P. Valadez-Cosmes, M. Kathrin, O. Kindler, N. Cosic-Mujkanovic, A. Lueger, S. Raftopoulou, M. Kienzl, Z. N. Mihalic, A. Santiso, A. Sarsembayeva, L. Brcic, J. Lindenmann, W. Sattler, A. Heinemann, R. Schicho, , J. Kargl

The paper shows high MPO expression in NSCLC predicts poor outcomes and MPO deficiency in mice enhances anti-tumorigenic immune infiltration, suggesting MPO promotes a pro-tumorigenic microenvironment.

bioRxiv · Jan 28, 2023Cancer Biology

Loss of MGA mediated Polycomb repression promotes tumor progression and invasiveness

H. Mathsyaraja, J. Catchpole, E. Eastwood, E. Babaeva, M. J. Geuenich, P.-F. Cheng, B. Freie, J. L. Ayers, M. Yu, N. Wu, K. R. Poudel, A. Koehne, W. Grady, A. M. Houghton, Y. Shiio, , R. N. Eisenman

This study shows that loss of MGA promotes tumor growth and invasiveness by de-repressing Polycomb targets in lung and colon cancers.

eLife · Jul 8, 2021Peer-reviewedCancer Biology