The Aedes aegypti peritrophic matrix controls arbovirus vector competence through HPx1, a heme induced peroxidase.
O. A. C. Talyuli, J. H. M. Oliveira, V. Bottino-Rojas, G. O. Silveira, P. H. Alvarenga, A. M. Kantor, G. O. Paiva-SIlva, C. Barillas-Mury, P. L. Oliveira
This study identifies HPx1, a heme-induced peroxidase in Aedes aegypti, which regulates the peritrophic matrix and influences vector competence for arboviruses by modulating ROS and microbiota.
bioRxiv · Jun 2, 2022Microbiology