Author

A. M. Laughney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

L. C. Cantley· 2 shared B. D. Hopkins· 1 shared B. D. Stein· 1 shared C. Liu· 1 shared C. Louka· 1 shared C. Zhang· 1 shared D. D. Giri· 1 shared D. J. Byun· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

L. C. Cantley

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Lineage-specific intolerance to oncogenic drivers restricts histological transformation

E. E. Gardner, E. M. Earlie, K. Li, J. Thomas, M. J. Hubisz, B. D. Stein, C. Zhang, L. C. Cantley, A. M. Laughney, H. Varmus

The paper models histological transformation of lung cancer and identifies neuroendocrine-specific tolerance to Myc as an oncogenic driver.

bioRxiv · Jun 21, 2023Cancer Biology

Obesity promotes breast epithelium DNA damage in BRCA mutation carriers

P. Bhardwaj, N. M. Iyengar, H. Zahid, K. M. Carter, D. J. Byun, M.-H. Choi, Q. Sun, O. Savenkov, C. Louka, C. Liu, P. Piloco, M. Acosta, R. Bareja, O. Elemento, M. Foronda, , K. A. Brown

The paper shows that obesity increases DNA damage in breast epithelium of BRCA mutation carriers and suggests targeting estrogen or metabolic dysfunction may reduce breast cancer risk.

bioRxiv · Jul 29, 2022 · PreprintCancer Biology