Exploration of the single-cell transcriptomic landscape identifies aberrant glomerular cell crosstalk in a murine model of WT1 kidney disease
J. C. Chandler, D. J. Jafree, S. Malik, G. Pomeranz, M. Ball, M. Kolatsi-Joannou, A. Piapi, W. J. Mason, A. S. Woolf, P. J. Winyard, A. S. Mason, A. M. Waters, D. A. Long
This study uses single-cell RNA sequencing to identify disrupted cell-cell communication in a mouse model of WT1 kidney disease, highlighting non-immunological pathology and suggesting vascular-targeted therapies.
bioRxiv · Oct 11, 2022 · PreprintCell Biology